CaMKIIβ/γ/δ (Phospho Thr287) Monoclonal Antibody(4H2)

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商品货号： PLA005803

适应性： 人,大鼠,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

Human_gene_id： 816/817/818
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=816/817/818
Human_swiss_prot_no： Q13554/Q13555/Q13557
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13554/Q13555/Q13557/entry
特异性： CaMKIIβ/γ/δ (Phospho Thr287) protein detects endogenous levels of CaMKIIβ/γ/δ (Phospho Thr287)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Monoclonal, Mouse
稀释： IHC 1:100-200. IF 1:50-200
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CAMK2B; CAM2; CAMK2; CAMKB; Calcium/calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/calmodulin-dependent protein kinase type II subunit gamma;
实测条带： 50kD
信号通路： ErbB_HER;Calcium;Oocyte meiosis;WNT;WNT-T CELLLong-term potentiation;Neurotrophin;Olfactory transduction;GnRH;Melanogenesis;Glioma;
功能： alternative products:The variable region of the CAMK2B protein is encoded by at least 7 exons (V1 to V7). Alternative splicing within this region gives rise to CAMK2B isoforms,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Autophosphorylation of CAMK2 plays an important role in the regulation of the kinase activity.,function:CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,subunit:CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Interacts with SYNGAP1 and CAMK2N2 (By similarity). Interacts with MPDZ.,tissue specificity:Widely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse . In slow-twitch muscle, evenly distributed between longitudinal SR and junctional SR.
组织表达： Widely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain. Expressed in skeletal muscle.
科研货号： PLA005803

CaMKIIβ/γ/δ (Phospho Thr287) Monoclonal Antibody(4H2)

Catalog No PLA005803

Product information

Human_gene_id： 816/817/818
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=816/817/818
Human_swiss_prot_no： Q13554/Q13555/Q13557
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13554/Q13555/Q13557/entry
特异性： CaMKIIβ/γ/δ (Phospho Thr287) protein detects endogenous levels of CaMKIIβ/γ/δ (Phospho Thr287)
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Monoclonal, Mouse
稀释： IHC 1:100-200. IF 1:50-200
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CAMK2B; CAM2; CAMK2; CAMKB; Calcium/calmodulin-dependent protein kinase type II subunit beta; CaM kinase II subunit beta; CaMK-II subunit beta; CAMK2G; CAMK; CAMK-II; CAMKG; Calcium/calmodulin-dependent protein kinase type II subunit gamma;
实测条带： 50kD
信号通路： ErbB_HER;Calcium;Oocyte meiosis;WNT;WNT-T CELLLong-term potentiation;Neurotrophin;Olfactory transduction;GnRH;Melanogenesis;Glioma;
功能： alternative products:The variable region of the CAMK2B protein is encoded by at least 7 exons (V1 to V7). Alternative splicing within this region gives rise to CAMK2B isoforms,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Autophosphorylation of CAMK2 plays an important role in the regulation of the kinase activity.,function:CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,subunit:CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Interacts with SYNGAP1 and CAMK2N2 (By similarity). Interacts with MPDZ.,tissue specificity:Widely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse . In slow-twitch muscle, evenly distributed between longitudinal SR and junctional SR.
组织表达： Widely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain. Expressed in skeletal muscle.
科研货号： PLA005803

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