Peroxiredoxin 1 Monoclonal Antibody(8E7)

> > > >

商品货号： PLA005668

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

在线咨询

MSDS

说明书

商品描述

基因名称： PRDX1
蛋白名称： Peroxiredoxin-1
Human_gene_id： 5052
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5052
Human_swiss_prot_no： Q06830
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q06830/entry
Mouse_gene_id： 18477
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18477
Mouse_swiss_prot_no： P35700
Mouse_swiss_link： http://www.uniprot.org/uniprot/P35700
Rat_gene_id： 117254
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=117254
Rat_swiss_prot_no： Q63716
Rat_swiss_link： http://www.uniprot.org/uniprot/Q63716
特异性： The antibody detects endogenous Peroxiredoxin 1 protein.
组成： PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
来源： Monoclonal, Mouse
稀释： WB 1:1000-3000 IF 1:100-200 IHC 1:50-300
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： PRDX1; PAGA; PAGB; TDPX2; Peroxiredoxin-1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2
实测条带： 21kD
功能： catalytic activity:2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.,function:Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).,induction:Constitutively expressed in most human cells; is induced to higher levels upon serum stimulation in untransformed and transformed cells.,miscellaneous:Inactivated upon oxidative stress by overoxidation of Cys-52 to Cys-SO(2)H and Cys-SO(3)H. Cys-SO(2)H is retroreduced to Cys-SOH after removal of H(2)O(2), while Cys-SO(3)H may be irreversibly oxidized.,miscellaneous:The active site is the redox-active Cys-52 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-173-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.,PTM:Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity.,similarity:Belongs to the ahpC/TSA family.,similarity:Contains 1 thioredoxin domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer; disulfide-linked, upon oxidation (By similarity). May form heterodimers with AOP2.,
相关产品： YT5455,YM3349,YM3112,RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
组织表达： Brain,Cajal-Retzius cell,Fetal brain cortex,Urinary bladder,
tag： hot
科研货号： PLA005668

Peroxiredoxin 1 Monoclonal Antibody(8E7)

Catalog No PLA005668

Product information

基因名称： PRDX1
蛋白名称： Peroxiredoxin-1
Human_gene_id： 5052
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5052
Human_swiss_prot_no： Q06830
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q06830/entry
Mouse_gene_id： 18477
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18477
Mouse_swiss_prot_no： P35700
Mouse_swiss_link： http://www.uniprot.org/uniprot/P35700
Rat_gene_id： 117254
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=117254
Rat_swiss_prot_no： Q63716
Rat_swiss_link： http://www.uniprot.org/uniprot/Q63716
特异性： The antibody detects endogenous Peroxiredoxin 1 protein.
组成： PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
来源： Monoclonal, Mouse
稀释： WB 1:1000-3000 IF 1:100-200 IHC 1:50-300
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： PRDX1; PAGA; PAGB; TDPX2; Peroxiredoxin-1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2
实测条带： 21kD
功能： catalytic activity:2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.,function:Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).,induction:Constitutively expressed in most human cells; is induced to higher levels upon serum stimulation in untransformed and transformed cells.,miscellaneous:Inactivated upon oxidative stress by overoxidation of Cys-52 to Cys-SO(2)H and Cys-SO(3)H. Cys-SO(2)H is retroreduced to Cys-SOH after removal of H(2)O(2), while Cys-SO(3)H may be irreversibly oxidized.,miscellaneous:The active site is the redox-active Cys-52 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-173-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.,PTM:Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity.,similarity:Belongs to the ahpC/TSA family.,similarity:Contains 1 thioredoxin domain.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer; disulfide-linked, upon oxidation (By similarity). May form heterodimers with AOP2.,
相关产品： YT5455,YM3349,YM3112,RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
组织表达： Brain,Cajal-Retzius cell,Fetal brain cortex,Urinary bladder,
tag： hot
科研货号： PLA005668

Hunan UPT Biotechnology Co.,Ltd

Website：www.uptbio.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.