β-actin Monoclonal Antibody(5B7), AbFluor™ 488 Conjugated

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商品货号： PLA005568

适应性： 人,大鼠,小鼠,猴,狗,鸡,仓鼠,兔,昆虫

￥600元

规格：

40μL 100μL 200μL

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说明书

商品描述

发货日期： 14
基因名称： ACTB
蛋白名称： Actin cytoplasmic 1
Human_gene_id： 60
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60
Human_swiss_prot_no： P60709
Human_swiss_link： https://www.uniprot.org/uniprotkb/P60709/entry
特异性： β-actin Monoclonal Antibody(5B7) AbFluor™ 488 Conjugated specially designed for your Immunofluorescence analysis.
组成： Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
来源： Monoclonal, Mouse IgG1
稀释： Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:200, IF 1:200.
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度： 1mg/ml
储存： Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
说明书： 1
其他名称： ACTB
信号通路： Focal adhesion;Adherens_Junction;Adherens_Junction;Leukocyte transendothelial migration;Regulates Actin and Cytoskeleton;Vibrio cholerae infection;Pathogenic Escherichia coli infection;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;Viral myocarditis;
功能： disease:Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the actin family.,subunit:Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Interacts with XPO6.,
相关产品： YT0099,YN1902,YM3608,YM3607,YM3214,YM3138,YM3133,YM3121,YM3039,YM3032,YM3028,YM2195,YM2194,YM2193,YM2192,YM2191,YM2190,YM2189,YM2188,YM2187,YM2186,YM2185,YM2093,CM3028
细胞定位： Cytoplasm, cytoskeleton . Nucleus . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
组织表达： B-cell lymphoma,Brain,Cajal-Retzius cell,Eye,Fetal brain cortex,Foreskin,Hepatocellular car
科研货号： PLA005568

β-actin Monoclonal Antibody(5B7), AbFluor™ 488 Conjugated

Catalog No PLA005568

Product information

发货日期： 14
基因名称： ACTB
蛋白名称： Actin cytoplasmic 1
Human_gene_id： 60
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60
Human_swiss_prot_no： P60709
Human_swiss_link： https://www.uniprot.org/uniprotkb/P60709/entry
特异性： β-actin Monoclonal Antibody(5B7) AbFluor™ 488 Conjugated specially designed for your Immunofluorescence analysis.
组成： Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
来源： Monoclonal, Mouse IgG1
稀释： Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:200, IF 1:200.
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度： 1mg/ml
储存： Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
说明书： 1
其他名称： ACTB
信号通路： Focal adhesion;Adherens_Junction;Adherens_Junction;Leukocyte transendothelial migration;Regulates Actin and Cytoskeleton;Vibrio cholerae infection;Pathogenic Escherichia coli infection;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;Viral myocarditis;
功能： disease:Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the actin family.,subunit:Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Interacts with XPO6.,
相关产品： YT0099,YN1902,YM3608,YM3607,YM3214,YM3138,YM3133,YM3121,YM3039,YM3032,YM3028,YM2195,YM2194,YM2193,YM2192,YM2191,YM2190,YM2189,YM2188,YM2187,YM2186,YM2185,YM2093,CM3028
细胞定位： Cytoplasm, cytoskeleton . Nucleus . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. .
组织表达： B-cell lymphoma,Brain,Cajal-Retzius cell,Eye,Fetal brain cortex,Foreskin,Hepatocellular car
科研货号： PLA005568

Hunan UPT Biotechnology Co.,Ltd

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