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α-tubulin Monoclonal Antibody(8F11), FITC Conjugated
商品货号: PLA005564
适 应 性: 人,大鼠,小鼠
WB IHC IF IP
¥600元
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说明书
商品描述
  • 发货日期: 14
  • 基因名称: TUBA1A
  • 蛋白名称: Tubulin alpha-1A chain
  • Human_gene_id: 7846/10376
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7846
  • Human_swiss_prot_no: Q71U36/P68363
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/Q71U36/entry
  • 特异性: α-tubulin Monoclonal Antibody(8F11) FITC conjugated specially designed for your WB or IHC analysis.
  • 组成: Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
  • 来源: Monoclonal, Mouse IgG
  • 稀释: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300, IF 1:200.
  • 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • 浓度: 1mg/ml
  • 储存: Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
  • 说明书: 1
  • 其他名称: TUBA1A
  • 信号通路: Gap junction;Pathogenic Escherichia coli infection;
  • 功能: disease:Defects in TUBA1A are the cause of lissencephaly type 3 (LIS3) [MIM:611603]. LIS is characterized by a smooth brain surface due to the absence (agyria) or reduction (pachygyria) of surface convolutions. It is often associated with psychomotor retardation and seizures. LIS3 features include agyria or pachygyria or laminar heterotopia, severe mental retardation, motor delay, variable presence of seizures, and abnormalities of corpus callosum, hippocampus, cerebellar vermis and brainstem.,function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,tissue specificity:Expressed at a high level in fetal brain.,
  • 相关产品: YT5865,YT5051,YT4777,YM3217,YM3035,YM2184,YM2183,YM2182,YM2181,YM2180,YM2179,YM2178,YM2177,YM2176,YM2175,YM2174,YM2173,KA3421C,CM3035
  • 细胞定位: Cytoplasm, cytoskeleton.
  • 组织表达: Expressed at a high level in fetal brain.
  • 科研货号: PLA005564
α-tubulin Monoclonal Antibody(8F11), FITC Conjugated
Catalog No PLA005564
Product information
  • 发货日期: 14
  • 基因名称: TUBA1A
  • 蛋白名称: Tubulin alpha-1A chain
  • Human_gene_id: 7846/10376
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7846
  • Human_swiss_prot_no: Q71U36/P68363
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/Q71U36/entry
  • 特异性: α-tubulin Monoclonal Antibody(8F11) FITC conjugated specially designed for your WB or IHC analysis.
  • 组成: Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
  • 来源: Monoclonal, Mouse IgG
  • 稀释: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300, IF 1:200.
  • 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  • 浓度: 1mg/ml
  • 储存: Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Store in dark.
  • 说明书: 1
  • 其他名称: TUBA1A
  • 信号通路: Gap junction;Pathogenic Escherichia coli infection;
  • 功能: disease:Defects in TUBA1A are the cause of lissencephaly type 3 (LIS3) [MIM:611603]. LIS is characterized by a smooth brain surface due to the absence (agyria) or reduction (pachygyria) of surface convolutions. It is often associated with psychomotor retardation and seizures. LIS3 features include agyria or pachygyria or laminar heterotopia, severe mental retardation, motor delay, variable presence of seizures, and abnormalities of corpus callosum, hippocampus, cerebellar vermis and brainstem.,function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,tissue specificity:Expressed at a high level in fetal brain.,
  • 相关产品: YT5865,YT5051,YT4777,YM3217,YM3035,YM2184,YM2183,YM2182,YM2181,YM2180,YM2179,YM2178,YM2177,YM2176,YM2175,YM2174,YM2173,KA3421C,CM3035
  • 细胞定位: Cytoplasm, cytoskeleton.
  • 组织表达: Expressed at a high level in fetal brain.
  • 科研货号: PLA005564
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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