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XRCC1 mouse mAb
商品货号: PLA005333
适 应 性:
WB
¥600元
规格:
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MSDS
说明书
商品描述
  • 发货日期: 7
  • 基因名称: xrcc1
  • Human_gene_id: 7515
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7515
  • Human_swiss_prot_no: P18887
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P18887/entry
  • Mouse_swiss_prot_no: Q60596
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q60596
  • 特异性: This antibody detects endogenous levels of XRCC1 and does not cross-react with related proteins.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Monoclonal, Mouse
  • 稀释: wb dilution 1:1000
  • 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: DNA repair protein XRCC1;RCC;X ray repair complementing defective repair in chinese hamster;X ray repair complementing defective repair in chinese hamster cells 1;X ray Repair Complementing Defective Repair in Chinese Hamster Cells;X ray repair cross complementing protein 1;X ray repair, complementing defective, repair in Chinese hamster;X-ray repair cross-complementing protein 1;XRCC 1;Xrcc1;XRCC1_HUMAN.
  • 实测条带: 82kD
  • 信号通路: Base excision repair;
  • 功能: function:Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.,polymorphism:Carriers of the polymorphic Gln-399 allele may be at greater risk for tobacco- and age-related DNA damage.,PTM:Phosphorylation of Ser-371 causes dimer dissociation. Phosphorylation by CK2 promotes interaction with APTX and APLF.,PTM:Sumoylated.,similarity:Contains 2 BRCT domains.,subcellular location:Accumulates at sites of DNA damage.,subunit:Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3). Interacts with APTX and APLF.,
  • 相关产品: YT4917,YM1417,KA4327C,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .
  • 组织表达: Expressed in fibroblasts, retinal pigmented epithelial cells and lymphoblastoid cells (at protein level).
  • 科研货号: PLA005333
XRCC1 mouse mAb
Catalog No PLA005333
Product information
  • 发货日期: 7
  • 基因名称: xrcc1
  • Human_gene_id: 7515
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7515
  • Human_swiss_prot_no: P18887
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P18887/entry
  • Mouse_swiss_prot_no: Q60596
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q60596
  • 特异性: This antibody detects endogenous levels of XRCC1 and does not cross-react with related proteins.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Monoclonal, Mouse
  • 稀释: wb dilution 1:1000
  • 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: DNA repair protein XRCC1;RCC;X ray repair complementing defective repair in chinese hamster;X ray repair complementing defective repair in chinese hamster cells 1;X ray Repair Complementing Defective Repair in Chinese Hamster Cells;X ray repair cross complementing protein 1;X ray repair, complementing defective, repair in Chinese hamster;X-ray repair cross-complementing protein 1;XRCC 1;Xrcc1;XRCC1_HUMAN.
  • 实测条带: 82kD
  • 信号通路: Base excision repair;
  • 功能: function:Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.,polymorphism:Carriers of the polymorphic Gln-399 allele may be at greater risk for tobacco- and age-related DNA damage.,PTM:Phosphorylation of Ser-371 causes dimer dissociation. Phosphorylation by CK2 promotes interaction with APTX and APLF.,PTM:Sumoylated.,similarity:Contains 2 BRCT domains.,subcellular location:Accumulates at sites of DNA damage.,subunit:Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3). Interacts with APTX and APLF.,
  • 相关产品: YT4917,YM1417,KA4327C,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .
  • 组织表达: Expressed in fibroblasts, retinal pigmented epithelial cells and lymphoblastoid cells (at protein level).
  • 科研货号: PLA005333
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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