其他名称: TBL1Y; TBL1; F-box-like/WD repeat-containing protein TBL1Y; Transducin beta-like protein 1Y; Transducin-beta-like protein 1; Y-linked
信号通路: WNT;WNT-T CELL
功能: domain:The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.,function:F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.,similarity:Belongs to the WD repeat EBI family.,similarity:Contains 1 F-box-like domain.,similarity:Contains 1 LisH domain.,similarity:Contains 8 WD repeats.,subunit:Probable component of the N-Cor repressor complex and some E3 ubiquitin ligase complex.,tissue specificity:Fetal brain and prostate.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus .
组织表达: Fetal brain and prostate. Expressed in the cochlear spiral ganglion neurons, and in outer and inner hair cells (PubMed:30341416).
科研货号: PLA005159
TBL1Y Monoclonal Antibody
Catalog NoPLA005159
Product information
发货日期: 7
基因名称: TBL1Y
蛋白名称: F-box-like/WD repeat-containing protein TBL1Y
其他名称: TBL1Y; TBL1; F-box-like/WD repeat-containing protein TBL1Y; Transducin beta-like protein 1Y; Transducin-beta-like protein 1; Y-linked
信号通路: WNT;WNT-T CELL
功能: domain:The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.,function:F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.,similarity:Belongs to the WD repeat EBI family.,similarity:Contains 1 F-box-like domain.,similarity:Contains 1 LisH domain.,similarity:Contains 8 WD repeats.,subunit:Probable component of the N-Cor repressor complex and some E3 ubiquitin ligase complex.,tissue specificity:Fetal brain and prostate.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus .
组织表达: Fetal brain and prostate. Expressed in the cochlear spiral ganglion neurons, and in outer and inner hair cells (PubMed:30341416).