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IL-1α Monoclonal Antibody
商品货号: PLA004874
适 应 性:
WB ELISA
¥600元
规格:
在线咨询
MSDS
说明书
商品描述
  • 发货日期: 7
  • 基因名称: IL1A
  • 蛋白名称: Interleukin-1 alpha
  • Human_gene_id: 3552
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3552
  • Human_swiss_prot_no: P01583
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P01583/entry
  • Mouse_swiss_prot_no: P01582
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P01582
  • 特异性: IL-1α Monoclonal Antibody detects endogenous levels of IL-1α protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Monoclonal, Mouse
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: Affinity purification
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: IL1A; IL1F1; Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1
  • 信号通路: MAPK_ERK_Growth;MAPK_G_Protein;Cytokine-cytokine receptor interaction;Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;Hematopoietic cell lineage;Type I diabetes mellitus;Prion diseases;Graft-versus-host disease;
  • 功能: domain:The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.,function:Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.,online information:Interleukin-1 entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the IL-1 family.,subcellular location:The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.,subunit:Monomer.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Secreted . The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
  • 组织表达: Lung,
  • 科研货号: PLA004874
IL-1α Monoclonal Antibody
Catalog No PLA004874
Product information
  • 发货日期: 7
  • 基因名称: IL1A
  • 蛋白名称: Interleukin-1 alpha
  • Human_gene_id: 3552
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3552
  • Human_swiss_prot_no: P01583
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P01583/entry
  • Mouse_swiss_prot_no: P01582
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P01582
  • 特异性: IL-1α Monoclonal Antibody detects endogenous levels of IL-1α protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Monoclonal, Mouse
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: Affinity purification
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: IL1A; IL1F1; Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1
  • 信号通路: MAPK_ERK_Growth;MAPK_G_Protein;Cytokine-cytokine receptor interaction;Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;Hematopoietic cell lineage;Type I diabetes mellitus;Prion diseases;Graft-versus-host disease;
  • 功能: domain:The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.,function:Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.,online information:Interleukin-1 entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the IL-1 family.,subcellular location:The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.,subunit:Monomer.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Secreted . The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
  • 组织表达: Lung,
  • 科研货号: PLA004874
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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