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Glycogen Synthase 1 Monoclonal Antibody
商品货号: PLA004834
适 应 性:
WB ELISA FCM
¥600元
规格:
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MSDS
说明书
商品描述
  • 发货日期: 7
  • 基因名称: GYS1
  • 蛋白名称: Glycogen [starch] synthase muscle
  • Human_gene_id: 2997
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2997
  • Human_swiss_prot_no: P13807
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P13807/entry
  • Mouse_swiss_prot_no: Q9Z1E4
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9Z1E4
  • 特异性: Glycogen Synthase 1 Monoclonal Antibody detects endogenous levels of Glycogen Synthase 1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Monoclonal, Mouse
  • 稀释: WB 1:500 - 1:2000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: Affinity purification
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: GYS1; GYS; Glycogen [starch] synthase; muscle
  • 信号通路: Starch and sucrose metabolism;Insulin_Receptor;
  • 功能: catalytic activity:UDP-glucose ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).,disease:Defects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; also called muscle glycogen synthase deficiency. GSD0 is a metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.,enzyme regulation:Allosteric activation by glucose-6-phosphate. Phosphorylation reduces the activity towards UDP-glucose. When in the non-phosphorylated state, glycogen synthase does not require glucose-6-phosphate as an allosteric activator; when phosphorylated it does.,function:Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.,pathway:Glycan biosynthesis; glycogen biosynthesis.,similarity:Belongs to the glycosyltransferase 3 family.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: cytosol,membrane,inclusion body,
  • 组织表达: Endometrium,Heart,Kidney,Lymph,Muscle,Skin,
  • 科研货号: PLA004834
Glycogen Synthase 1 Monoclonal Antibody
Catalog No PLA004834
Product information
  • 发货日期: 7
  • 基因名称: GYS1
  • 蛋白名称: Glycogen [starch] synthase muscle
  • Human_gene_id: 2997
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2997
  • Human_swiss_prot_no: P13807
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P13807/entry
  • Mouse_swiss_prot_no: Q9Z1E4
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9Z1E4
  • 特异性: Glycogen Synthase 1 Monoclonal Antibody detects endogenous levels of Glycogen Synthase 1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Monoclonal, Mouse
  • 稀释: WB 1:500 - 1:2000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: Affinity purification
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: GYS1; GYS; Glycogen [starch] synthase; muscle
  • 信号通路: Starch and sucrose metabolism;Insulin_Receptor;
  • 功能: catalytic activity:UDP-glucose ((1->4)-alpha-D-glucosyl)(n) = UDP + ((1->4)-alpha-D-glucosyl)(n+1).,disease:Defects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; also called muscle glycogen synthase deficiency. GSD0 is a metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.,enzyme regulation:Allosteric activation by glucose-6-phosphate. Phosphorylation reduces the activity towards UDP-glucose. When in the non-phosphorylated state, glycogen synthase does not require glucose-6-phosphate as an allosteric activator; when phosphorylated it does.,function:Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.,pathway:Glycan biosynthesis; glycogen biosynthesis.,similarity:Belongs to the glycosyltransferase 3 family.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: cytosol,membrane,inclusion body,
  • 组织表达: Endometrium,Heart,Kidney,Lymph,Muscle,Skin,
  • 科研货号: PLA004834
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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