CD247 Monoclonal Antibody(4B10)

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商品货号： PLA004703

适应性： 人

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

发货日期： 7
基因名称： CD247
蛋白名称： T-cell surface glycoprotein CD3 zeta chain
Human_gene_id： 919
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=919
Human_swiss_prot_no： P20963
Human_swiss_link： http://www.uniprot.org/uniprotkb/P20963/entry
Mouse_swiss_prot_no： P24161
Mouse_swiss_link： http://www.uniprot.org/uniprot/P24161
特异性： CD247 Monoclonal Antibody detects endogenous levels of CD247 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Monoclonal, Mouse
稀释： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： Affinity purification
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247
信号通路： Natural killer cell mediated cytotoxicity;T_Cell_Receptor;
功能： disease:Defects in CD247 are a cause of primary T-cell immunodeficiency [MIM:610163]. Affected individuals suffer of recurrent infections. Patients T-cell counts are very low and B-cell counts are normal.,domain:The ITAM domains mediate interaction with SHB.,function:Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.,online information:CD247 mutation db,PTM:Phosphorylated on Tyr residues after T-cell receptor triggering.,similarity:Belongs to the CD3Z/FCER1G family.,similarity:Contains 3 ITAM domains.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3-zeta forms either homodimers or heterodimers with CD3-eta. Interacts with SLA and SLA2. Interacts with DOCK2 and TRAT1. Interacts with HIV-1 Nef protein. Interacts with SHB.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type I membrane protein.
组织表达： CD3Z is expressed in normal lymphoid tissue and in peripheral blood mononuclear cells (PBMCs) (PubMed:11722641).
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科研货号： PLA004703

CD247 Monoclonal Antibody(4B10)

Catalog No PLA004703

Product information

发货日期： 7
基因名称： CD247
蛋白名称： T-cell surface glycoprotein CD3 zeta chain
Human_gene_id： 919
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=919
Human_swiss_prot_no： P20963
Human_swiss_link： http://www.uniprot.org/uniprotkb/P20963/entry
Mouse_swiss_prot_no： P24161
Mouse_swiss_link： http://www.uniprot.org/uniprot/P24161
特异性： CD247 Monoclonal Antibody detects endogenous levels of CD247 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Monoclonal, Mouse
稀释： WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. Flow cytometry: 1:200 - 1:400. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： Affinity purification
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： CD247; CD3Z; T3Z; TCRZ; T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD antigen CD247
信号通路： Natural killer cell mediated cytotoxicity;T_Cell_Receptor;
功能： disease:Defects in CD247 are a cause of primary T-cell immunodeficiency [MIM:610163]. Affected individuals suffer of recurrent infections. Patients T-cell counts are very low and B-cell counts are normal.,domain:The ITAM domains mediate interaction with SHB.,function:Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.,online information:CD247 mutation db,PTM:Phosphorylated on Tyr residues after T-cell receptor triggering.,similarity:Belongs to the CD3Z/FCER1G family.,similarity:Contains 3 ITAM domains.,subunit:The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3-zeta forms either homodimers or heterodimers with CD3-eta. Interacts with SLA and SLA2. Interacts with DOCK2 and TRAT1. Interacts with HIV-1 Nef protein. Interacts with SHB.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type I membrane protein.
组织表达： CD3Z is expressed in normal lymphoid tissue and in peripheral blood mononuclear cells (PBMCs) (PubMed:11722641).
tag： hot
科研货号： PLA004703

Hunan UPT Biotechnology Co.,Ltd

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