PERM (light chain, Cleaved-Gly278) rabbit pAb

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商品货号： PLA004469

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： MPO
蛋白名称： PERM (light chain, Cleaved-Gly278)
Human_gene_id： 4353
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4353
Human_swiss_prot_no： P05164
Human_swiss_link： https://www.uniprot.org/uniprotkb/P05164/entry
Mouse_gene_id： 17523
Mouse_gene_link： https://www.uniprot.org/uniprot/17523
Mouse_swiss_prot_no： P11247
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P11247
特异性： This antibody detects endogenous levels of Human PERM (light chain, Cleaved-Gly278, protein was cleaved amino acid sequence between 278-279 )
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Myeloperoxidase (MPO;EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]
实测条带： 12 84 89kD
功能： catalytic activity:Cl(-) + H(2)O(2) = HOCl + 2 H(2)O.,catalytic activity:Donor + H(2)O(2) = oxidized donor + 2 H(2)O.,cofactor:Binds 1 calcium ion per heterodimer.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.,disease:Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.,function:Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.,online information:MPO mutation db,online information:Myeloperoxidase entry,similarity:Belongs to the peroxidase family. XPO subfamily.,subunit:Tetramer of two light chains and two heavy chains.,
相关产品： RS0001,RS0002,YM3028,YM3116
细胞定位： Lysosome.
科研货号： PLA004469

PERM (light chain, Cleaved-Gly278) rabbit pAb

Catalog No PLA004469

Product information

基因名称： MPO
蛋白名称： PERM (light chain, Cleaved-Gly278)
Human_gene_id： 4353
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4353
Human_swiss_prot_no： P05164
Human_swiss_link： https://www.uniprot.org/uniprotkb/P05164/entry
Mouse_gene_id： 17523
Mouse_gene_link： https://www.uniprot.org/uniprot/17523
Mouse_swiss_prot_no： P11247
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P11247
特异性： This antibody detects endogenous levels of Human PERM (light chain, Cleaved-Gly278, protein was cleaved amino acid sequence between 278-279 )
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Myeloperoxidase (MPO;EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]
实测条带： 12 84 89kD
功能： catalytic activity:Cl(-) + H(2)O(2) = HOCl + 2 H(2)O.,catalytic activity:Donor + H(2)O(2) = oxidized donor + 2 H(2)O.,cofactor:Binds 1 calcium ion per heterodimer.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.,disease:Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.,function:Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.,online information:MPO mutation db,online information:Myeloperoxidase entry,similarity:Belongs to the peroxidase family. XPO subfamily.,subunit:Tetramer of two light chains and two heavy chains.,
相关产品： RS0001,RS0002,YM3028,YM3116
细胞定位： Lysosome.
科研货号： PLA004469

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