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PERM (light chain, Cleaved-Gly278) rabbit pAb
商品货号: PLA004469
适 应 性: 人,大鼠,小鼠,
WB IHC
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: MPO
  • 蛋白名称: PERM (light chain, Cleaved-Gly278)
  • Human_gene_id: 4353
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4353
  • Human_swiss_prot_no: P05164
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P05164/entry
  • Mouse_gene_id: 17523
  • Mouse_gene_link: https://www.uniprot.org/uniprot/17523
  • Mouse_swiss_prot_no: P11247
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/P11247
  • 特异性: This antibody detects endogenous levels of Human PERM (light chain, Cleaved-Gly278, protein was cleaved amino acid sequence between 278-279 )
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000;IHC-p 1:50-300
  • 纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Myeloperoxidase (MPO;EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]
  • 实测条带: 12 84 89kD
  • 功能: catalytic activity:Cl(-) + H(2)O(2) = HOCl + 2 H(2)O.,catalytic activity:Donor + H(2)O(2) = oxidized donor + 2 H(2)O.,cofactor:Binds 1 calcium ion per heterodimer.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.,disease:Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.,function:Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.,online information:MPO mutation db,online information:Myeloperoxidase entry,similarity:Belongs to the peroxidase family. XPO subfamily.,subunit:Tetramer of two light chains and two heavy chains.,
  • 相关产品: RS0001,RS0002,YM3028,YM3116
  • 细胞定位: Lysosome.
  • 科研货号: PLA004469
PERM (light chain, Cleaved-Gly278) rabbit pAb
Catalog No PLA004469
Product information
  • 基因名称: MPO
  • 蛋白名称: PERM (light chain, Cleaved-Gly278)
  • Human_gene_id: 4353
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4353
  • Human_swiss_prot_no: P05164
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P05164/entry
  • Mouse_gene_id: 17523
  • Mouse_gene_link: https://www.uniprot.org/uniprot/17523
  • Mouse_swiss_prot_no: P11247
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/P11247
  • 特异性: This antibody detects endogenous levels of Human PERM (light chain, Cleaved-Gly278, protein was cleaved amino acid sequence between 278-279 )
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000;IHC-p 1:50-300
  • 纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Myeloperoxidase (MPO;EC 1.11.2.2) [Cleaved into: Myeloperoxidase; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain]
  • 实测条带: 12 84 89kD
  • 功能: catalytic activity:Cl(-) + H(2)O(2) = HOCl + 2 H(2)O.,catalytic activity:Donor + H(2)O(2) = oxidized donor + 2 H(2)O.,cofactor:Binds 1 calcium ion per heterodimer.,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer.,disease:Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.,function:Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.,online information:MPO mutation db,online information:Myeloperoxidase entry,similarity:Belongs to the peroxidase family. XPO subfamily.,subunit:Tetramer of two light chains and two heavy chains.,
  • 相关产品: RS0001,RS0002,YM3028,YM3116
  • 细胞定位: Lysosome.
  • 科研货号: PLA004469
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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