特异性: This antibody detects endogenous levels of Human,Mouse,Rat HABP2 (50k heavy chain, Cleaved-Arg313, protein was cleaved amino acid sequence between 313-314 )
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Polyclonal, Rabbit,IgG
稀释: WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度: 1 mg/ml
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
其他名称: Hyaluronan-binding protein 2 (EC 3.4.21.-;Factor VII-activating protease;Factor seven-activating protease;FSAP;Hepatocyte growth factor activator-like protein;Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form]
实测条带: 50 77kD
功能: function:Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII.,PTM:Proteolytic cleavage at Gly-23 or Met-27 can give rise to the 50 kDa heavy chain and cleavage at Arg-313 or Lys-319 can give rise to the 27 kDa light chain. The heavy chain can undergo further proteolytic cleavage at Lys-169 or Arg-170 to give rise to 2 inactive 26 kDa fragments and the light chain can undergo further proteolytic cleavage at Arg-480 to give rise to inactive 17 kDa and 8 kDa fragments.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 kringle domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 3 EGF-like domains.,subcellular location:Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.,subunit:Heterodimer; disulfide-linked. Heterodimer of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond.,tissue specificity:Ubiquitously expressed.,
相关产品: RS0001,RS0002,YM3028,YM3087
细胞定位: Secreted . Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
组织表达: Ubiquitously expressed.
科研货号: PLA004440
HABP2 (50k heavy chain, Cleaved-Arg313) rabbit pAb
特异性: This antibody detects endogenous levels of Human,Mouse,Rat HABP2 (50k heavy chain, Cleaved-Arg313, protein was cleaved amino acid sequence between 313-314 )
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Polyclonal, Rabbit,IgG
稀释: WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度: 1 mg/ml
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
其他名称: Hyaluronan-binding protein 2 (EC 3.4.21.-;Factor VII-activating protease;Factor seven-activating protease;FSAP;Hepatocyte growth factor activator-like protein;Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form]
实测条带: 50 77kD
功能: function:Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII.,PTM:Proteolytic cleavage at Gly-23 or Met-27 can give rise to the 50 kDa heavy chain and cleavage at Arg-313 or Lys-319 can give rise to the 27 kDa light chain. The heavy chain can undergo further proteolytic cleavage at Lys-169 or Arg-170 to give rise to 2 inactive 26 kDa fragments and the light chain can undergo further proteolytic cleavage at Arg-480 to give rise to inactive 17 kDa and 8 kDa fragments.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 kringle domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 3 EGF-like domains.,subcellular location:Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.,subunit:Heterodimer; disulfide-linked. Heterodimer of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond.,tissue specificity:Ubiquitously expressed.,
相关产品: RS0001,RS0002,YM3028,YM3087
细胞定位: Secreted . Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.