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GGT1 (light chain, Cleaved-Thr381) rabbit pAb
商品货号: PLA004439
适 应 性: 人,大鼠,小鼠,
WB ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: GGT1 GGT
  • 蛋白名称: GGT1 (light chain, Cleaved-Thr381)
  • Human_gene_id: 2678
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2678
  • Human_swiss_prot_no: P19440
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P19440/entry
  • Mouse_gene_id: 14598
  • Mouse_gene_link: https://www.uniprot.org/uniprot/14598
  • Mouse_swiss_prot_no: Q60928
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q60928
  • Rat_gene_id: 116568
  • Rat_gene_link: https://www.uniprot.org/uniprot/116568
  • Rat_swiss_prot_no: P07314
  • Rat_swiss_link: https://www.uniprot.org/uniprotkb/P07314
  • 特异性: This antibody detects endogenous levels of Human GGT1 (light chain, Cleaved-Thr381, protein was cleaved amino acid sequence between 380-381 )
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:1000-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Gamma-glutamyltranspeptidase 1 (GGT 1;EC 2.3.2.2;Gamma-glutamyltransferase 1;Glutathione hydrolase 1;EC 3.4.19.13;Leukotriene-C4 hydrolase;EC 3.4.19.14;CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain]
  • 实测条带: 16 62kD
  • 功能: catalytic activity:(5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid.,disease:Defects in GGT1 are a cause of glutathionuria [MIM:231950]; also known as gamma-glutamyltranspeptidase deficiency. It is an autosomal recessive disease.,function:Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive.,function:Initiates extracellular glutathione (GSH) breakdown; catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors.,miscellaneous:Corresponds to the light chain of other gamma-glutamyltransferase family members.,miscellaneous:Cys-454 was thought to bind the gamma-glutamyl moiety, but mutagenesis of this residue had no effect on activity.,online information:Gamma-glutamyl transpeptidase entry,pathway:Sulfur metabolism; glutathione metabolism.,PTM:N-glycosylated on both chains. Contains hexoses, hexosamines and sialic acid residues. It is not known if the sialic acid residues are present on N-linked or on O-linked glycans.,similarity:Belongs to the gamma-glutamyltransferase family.,subunit:Heterodimer composed of the light and heavy chains. The active site is located in the light chain.,tissue specificity:Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.,tissue specificity:Highly expressed in fetal and adult kidney and liver.,
  • 相关产品: RS0001,RS0002,YM3028,YM3086
  • 细胞定位: Cell membrane ; Single-pass type II membrane protein .
  • 组织表达: Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.; [Isoform 3]: Lung-specific.
  • 科研货号: PLA004439
GGT1 (light chain, Cleaved-Thr381) rabbit pAb
Catalog No PLA004439
Product information
  • 基因名称: GGT1 GGT
  • 蛋白名称: GGT1 (light chain, Cleaved-Thr381)
  • Human_gene_id: 2678
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2678
  • Human_swiss_prot_no: P19440
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P19440/entry
  • Mouse_gene_id: 14598
  • Mouse_gene_link: https://www.uniprot.org/uniprot/14598
  • Mouse_swiss_prot_no: Q60928
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q60928
  • Rat_gene_id: 116568
  • Rat_gene_link: https://www.uniprot.org/uniprot/116568
  • Rat_swiss_prot_no: P07314
  • Rat_swiss_link: https://www.uniprot.org/uniprotkb/P07314
  • 特异性: This antibody detects endogenous levels of Human GGT1 (light chain, Cleaved-Thr381, protein was cleaved amino acid sequence between 380-381 )
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:1000-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Gamma-glutamyltranspeptidase 1 (GGT 1;EC 2.3.2.2;Gamma-glutamyltransferase 1;Glutathione hydrolase 1;EC 3.4.19.13;Leukotriene-C4 hydrolase;EC 3.4.19.14;CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain]
  • 实测条带: 16 62kD
  • 功能: catalytic activity:(5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid.,disease:Defects in GGT1 are a cause of glutathionuria [MIM:231950]; also known as gamma-glutamyltranspeptidase deficiency. It is an autosomal recessive disease.,function:Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive.,function:Initiates extracellular glutathione (GSH) breakdown; catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors.,miscellaneous:Corresponds to the light chain of other gamma-glutamyltransferase family members.,miscellaneous:Cys-454 was thought to bind the gamma-glutamyl moiety, but mutagenesis of this residue had no effect on activity.,online information:Gamma-glutamyl transpeptidase entry,pathway:Sulfur metabolism; glutathione metabolism.,PTM:N-glycosylated on both chains. Contains hexoses, hexosamines and sialic acid residues. It is not known if the sialic acid residues are present on N-linked or on O-linked glycans.,similarity:Belongs to the gamma-glutamyltransferase family.,subunit:Heterodimer composed of the light and heavy chains. The active site is located in the light chain.,tissue specificity:Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.,tissue specificity:Highly expressed in fetal and adult kidney and liver.,
  • 相关产品: RS0001,RS0002,YM3028,YM3086
  • 细胞定位: Cell membrane ; Single-pass type II membrane protein .
  • 组织表达: Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.; [Isoform 3]: Lung-specific.
  • 科研货号: PLA004439
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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