GGT1 (light chain, Cleaved-Thr381) rabbit pAb

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商品货号： PLA004439

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： GGT1 GGT
蛋白名称： GGT1 (light chain, Cleaved-Thr381)
Human_gene_id： 2678
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2678
Human_swiss_prot_no： P19440
Human_swiss_link： https://www.uniprot.org/uniprotkb/P19440/entry
Mouse_gene_id： 14598
Mouse_gene_link： https://www.uniprot.org/uniprot/14598
Mouse_swiss_prot_no： Q60928
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q60928
Rat_gene_id： 116568
Rat_gene_link： https://www.uniprot.org/uniprot/116568
Rat_swiss_prot_no： P07314
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P07314
特异性： This antibody detects endogenous levels of Human GGT1 (light chain, Cleaved-Thr381, protein was cleaved amino acid sequence between 380-381 )
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Gamma-glutamyltranspeptidase 1 (GGT 1;EC 2.3.2.2;Gamma-glutamyltransferase 1;Glutathione hydrolase 1;EC 3.4.19.13;Leukotriene-C4 hydrolase;EC 3.4.19.14;CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain]
实测条带： 16 62kD
功能： catalytic activity:(5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid.,disease:Defects in GGT1 are a cause of glutathionuria [MIM:231950]; also known as gamma-glutamyltranspeptidase deficiency. It is an autosomal recessive disease.,function:Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive.,function:Initiates extracellular glutathione (GSH) breakdown; catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors.,miscellaneous:Corresponds to the light chain of other gamma-glutamyltransferase family members.,miscellaneous:Cys-454 was thought to bind the gamma-glutamyl moiety, but mutagenesis of this residue had no effect on activity.,online information:Gamma-glutamyl transpeptidase entry,pathway:Sulfur metabolism; glutathione metabolism.,PTM:N-glycosylated on both chains. Contains hexoses, hexosamines and sialic acid residues. It is not known if the sialic acid residues are present on N-linked or on O-linked glycans.,similarity:Belongs to the gamma-glutamyltransferase family.,subunit:Heterodimer composed of the light and heavy chains. The active site is located in the light chain.,tissue specificity:Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.,tissue specificity:Highly expressed in fetal and adult kidney and liver.,
相关产品： RS0001,RS0002,YM3028,YM3086
细胞定位： Cell membrane ; Single-pass type II membrane protein .
组织表达： Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.; [Isoform 3]: Lung-specific.
科研货号： PLA004439

GGT1 (light chain, Cleaved-Thr381) rabbit pAb

Catalog No PLA004439

Product information

基因名称： GGT1 GGT
蛋白名称： GGT1 (light chain, Cleaved-Thr381)
Human_gene_id： 2678
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2678
Human_swiss_prot_no： P19440
Human_swiss_link： https://www.uniprot.org/uniprotkb/P19440/entry
Mouse_gene_id： 14598
Mouse_gene_link： https://www.uniprot.org/uniprot/14598
Mouse_swiss_prot_no： Q60928
Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q60928
Rat_gene_id： 116568
Rat_gene_link： https://www.uniprot.org/uniprot/116568
Rat_swiss_prot_no： P07314
Rat_swiss_link： https://www.uniprot.org/uniprotkb/P07314
特异性： This antibody detects endogenous levels of Human GGT1 (light chain, Cleaved-Thr381, protein was cleaved amino acid sequence between 380-381 )
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:1000-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： Gamma-glutamyltranspeptidase 1 (GGT 1;EC 2.3.2.2;Gamma-glutamyltransferase 1;Glutathione hydrolase 1;EC 3.4.19.13;Leukotriene-C4 hydrolase;EC 3.4.19.14;CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain]
实测条带： 16 62kD
功能： catalytic activity:(5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid.,disease:Defects in GGT1 are a cause of glutathionuria [MIM:231950]; also known as gamma-glutamyltranspeptidase deficiency. It is an autosomal recessive disease.,function:Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive.,function:Initiates extracellular glutathione (GSH) breakdown; catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors.,miscellaneous:Corresponds to the light chain of other gamma-glutamyltransferase family members.,miscellaneous:Cys-454 was thought to bind the gamma-glutamyl moiety, but mutagenesis of this residue had no effect on activity.,online information:Gamma-glutamyl transpeptidase entry,pathway:Sulfur metabolism; glutathione metabolism.,PTM:N-glycosylated on both chains. Contains hexoses, hexosamines and sialic acid residues. It is not known if the sialic acid residues are present on N-linked or on O-linked glycans.,similarity:Belongs to the gamma-glutamyltransferase family.,subunit:Heterodimer composed of the light and heavy chains. The active site is located in the light chain.,tissue specificity:Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.,tissue specificity:Highly expressed in fetal and adult kidney and liver.,
相关产品： RS0001,RS0002,YM3028,YM3086
细胞定位： Cell membrane ; Single-pass type II membrane protein .
组织表达： Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.; [Isoform 3]: Lung-specific.
科研货号： PLA004439

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