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FA11 (heavy chain, Cleaved-Glu19) rabbit pAb
商品货号: PLA004406
适 应 性: 人,小鼠
WB ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: F11
  • 蛋白名称: FA11 (heavy chain, Cleaved-Glu19)
  • Human_gene_id: 2160
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2160
  • Human_swiss_prot_no: P03951
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P03951/entry
  • Mouse_gene_id: 109821
  • Mouse_gene_link: https://www.uniprot.org/uniprot/109821
  • Mouse_swiss_prot_no: Q91Y47
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q91Y47
  • 特异性: This antibody detects endogenous levels of Human, Mouse FA11 (heavy chain, Cleaved-Glu19, protein was cleaved amino acid sequence between 18-19 )
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:1000-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Coagulation factor XI (FXI;EC 3.4.21.27;Plasma thromboplastin antecedent;PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain]
  • 实测条带: 40 66kD
  • 功能: catalytic activity:Selective cleavage of Arg-|-Ala and Arg-|-Val bonds in factor IX to form factor IXa.,disease:Defects in F11 are the cause of F11 deficiency [MIM:612416]; also called plasma thromboplastin antecedent deficiency or Rosenthal syndrome. It is a blood coagulation abnormality occurring in high frequency in Ashkenazi jews. F11-deficient patients are prone to excessive bleeding after haemostatic challenge.,function:Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.,online information:Factor XI entry,PTM:Activated by factor XIIa (or XII), which cleaves each polypeptide after Arg-387 into the light chain, which contains the active site, and the heavy chain, which associates with high molecular weight (HMW) kininogen.,similarity:Belongs to the peptidase S1 family. Plasma kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 4 apple domains.,subunit:Homodimer; disulfide-linked. After activation the heavy and light chains are also linked by a disulfide bond.,tissue specificity:Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.,
  • 相关产品: RS0001,RS0002,YM3028,YM3053
  • 细胞定位: Secreted.
  • 组织表达: Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.
  • 科研货号: PLA004406
FA11 (heavy chain, Cleaved-Glu19) rabbit pAb
Catalog No PLA004406
Product information
  • 基因名称: F11
  • 蛋白名称: FA11 (heavy chain, Cleaved-Glu19)
  • Human_gene_id: 2160
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2160
  • Human_swiss_prot_no: P03951
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P03951/entry
  • Mouse_gene_id: 109821
  • Mouse_gene_link: https://www.uniprot.org/uniprot/109821
  • Mouse_swiss_prot_no: Q91Y47
  • Mouse_swiss_link: https://www.uniprot.org/uniprotkb/Q91Y47
  • 特异性: This antibody detects endogenous levels of Human, Mouse FA11 (heavy chain, Cleaved-Glu19, protein was cleaved amino acid sequence between 18-19 )
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:1000-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: Coagulation factor XI (FXI;EC 3.4.21.27;Plasma thromboplastin antecedent;PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain]
  • 实测条带: 40 66kD
  • 功能: catalytic activity:Selective cleavage of Arg-|-Ala and Arg-|-Val bonds in factor IX to form factor IXa.,disease:Defects in F11 are the cause of F11 deficiency [MIM:612416]; also called plasma thromboplastin antecedent deficiency or Rosenthal syndrome. It is a blood coagulation abnormality occurring in high frequency in Ashkenazi jews. F11-deficient patients are prone to excessive bleeding after haemostatic challenge.,function:Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.,online information:Factor XI entry,PTM:Activated by factor XIIa (or XII), which cleaves each polypeptide after Arg-387 into the light chain, which contains the active site, and the heavy chain, which associates with high molecular weight (HMW) kininogen.,similarity:Belongs to the peptidase S1 family. Plasma kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 4 apple domains.,subunit:Homodimer; disulfide-linked. After activation the heavy and light chains are also linked by a disulfide bond.,tissue specificity:Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.,
  • 相关产品: RS0001,RS0002,YM3028,YM3053
  • 细胞定位: Secreted.
  • 组织表达: Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells.
  • 科研货号: PLA004406
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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