Cleaved-Thrombin R (S42) Polyclonal Antibody

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商品货号： PLA004379

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： F2R
蛋白名称： Proteinase-activated receptor 1
Human_gene_id： 2149
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2149
Human_swiss_prot_no： P25116
Human_swiss_link： http://www.uniprot.org/uniprotkb/P25116/entry
Mouse_swiss_prot_no： P30558
Mouse_swiss_link： http://www.uniprot.org/uniprot/P30558
特异性： Cleaved-Thrombin R (S42) Polyclonal Antibody detects endogenous levels of fragment of activated Thrombin R protein resulting from cleavage adjacent to S42.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： F2R; CF2R; PAR1; TR; Proteinase-activated receptor 1; PAR-1; Coagulation factor II receptor; Thrombin receptor
实测条带： 46kD
信号通路： Calcium;Neuroactive ligand-receptor interaction;Endocytosis;Complement and coagulation cascades;Regulates Actin and Cytoskeleton;
功能： function:High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.,PTM:A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.,PTM:Phosphorylated; probably mediating desensitization prior to the uncoupling and internalization of the receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Platelets and vascular endothelial cells.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Multi-pass membrane protein.
组织表达： Platelets and vascular endothelial cells.
科研货号： PLA004379

Cleaved-Thrombin R (S42) Polyclonal Antibody

Catalog No PLA004379

Product information

基因名称： F2R
蛋白名称： Proteinase-activated receptor 1
Human_gene_id： 2149
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2149
Human_swiss_prot_no： P25116
Human_swiss_link： http://www.uniprot.org/uniprotkb/P25116/entry
Mouse_swiss_prot_no： P30558
Mouse_swiss_link： http://www.uniprot.org/uniprot/P30558
特异性： Cleaved-Thrombin R (S42) Polyclonal Antibody detects endogenous levels of fragment of activated Thrombin R protein resulting from cleavage adjacent to S42.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： F2R; CF2R; PAR1; TR; Proteinase-activated receptor 1; PAR-1; Coagulation factor II receptor; Thrombin receptor
实测条带： 46kD
信号通路： Calcium;Neuroactive ligand-receptor interaction;Endocytosis;Complement and coagulation cascades;Regulates Actin and Cytoskeleton;
功能： function:High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.,PTM:A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.,PTM:Phosphorylated; probably mediating desensitization prior to the uncoupling and internalization of the receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Platelets and vascular endothelial cells.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane; Multi-pass membrane protein.
组织表达： Platelets and vascular endothelial cells.
科研货号： PLA004379

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