特异性: Cleaved-Thrombin R (S42) Polyclonal Antibody detects endogenous levels of fragment of activated Thrombin R protein resulting from cleavage adjacent to S42.
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Polyclonal, Rabbit,IgG
稀释: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度: 1 mg/ml
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
信号通路: Calcium;Neuroactive ligand-receptor interaction;Endocytosis;Complement and coagulation cascades;Regulates Actin and Cytoskeleton;
功能: function:High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.,PTM:A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.,PTM:Phosphorylated; probably mediating desensitization prior to the uncoupling and internalization of the receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Platelets and vascular endothelial cells.,
特异性: Cleaved-Thrombin R (S42) Polyclonal Antibody detects endogenous levels of fragment of activated Thrombin R protein resulting from cleavage adjacent to S42.
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Polyclonal, Rabbit,IgG
稀释: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度: 1 mg/ml
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
信号通路: Calcium;Neuroactive ligand-receptor interaction;Endocytosis;Complement and coagulation cascades;Regulates Actin and Cytoskeleton;
功能: function:High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.,PTM:A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.,PTM:Phosphorylated; probably mediating desensitization prior to the uncoupling and internalization of the receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Platelets and vascular endothelial cells.,