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Cleaved-Integrin αV HC (K889) Polyclonal Antibody
商品货号: PLA004367
适 应 性: 人,大鼠,小鼠,
WB ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: ITGAV
  • 蛋白名称: Integrin alpha-V
  • Human_gene_id: 3685
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3685
  • Human_swiss_prot_no: P06756
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P06756/entry
  • Mouse_swiss_prot_no: P43406
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P43406
  • 特异性: Cleaved-Integrin αV HC (K889) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin αV HC protein resulting from cleavage adjacent to K889.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ITGAV; MSK8; VNRA; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51
  • 实测条带: 95kD
  • 信号通路: Focal adhesion;ECM-receptor interaction;Cell adhesion molecules (CAMs);Regulates Actin and Cytoskeleton;Pathways in cancer;Small cell lung cancer;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;
  • 功能: function:The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8 subunit. Interacts with HIV-1 Tat. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus (By similarity). Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion .
  • 组织表达: Aortic endothelium,Liver,Pooled,Testis,
  • 科研货号: PLA004367
Cleaved-Integrin αV HC (K889) Polyclonal Antibody
Catalog No PLA004367
Product information
  • 基因名称: ITGAV
  • 蛋白名称: Integrin alpha-V
  • Human_gene_id: 3685
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3685
  • Human_swiss_prot_no: P06756
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P06756/entry
  • Mouse_swiss_prot_no: P43406
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P43406
  • 特异性: Cleaved-Integrin αV HC (K889) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin αV HC protein resulting from cleavage adjacent to K889.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ITGAV; MSK8; VNRA; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51
  • 实测条带: 95kD
  • 信号通路: Focal adhesion;ECM-receptor interaction;Cell adhesion molecules (CAMs);Regulates Actin and Cytoskeleton;Pathways in cancer;Small cell lung cancer;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;
  • 功能: function:The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8 subunit. Interacts with HIV-1 Tat. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus (By similarity). Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion .
  • 组织表达: Aortic endothelium,Liver,Pooled,Testis,
  • 科研货号: PLA004367
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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