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Cleaved-Integrin α5 LC (E895) Polyclonal Antibody
商品货号: PLA004364
适 应 性: 人,大鼠,小鼠,
WB ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: ITGA5
  • 蛋白名称: Integrin alpha-5
  • Human_gene_id: 3678
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3678
  • Human_swiss_prot_no: P08648
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P08648/entry
  • Mouse_swiss_prot_no: P11688
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P11688
  • 特异性: Cleaved-Integrin α5 LC (E895) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α5 LC protein resulting from cleavage adjacent to E895.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD antigen CD49e
  • 实测条带: 18kD
  • 信号通路: Focal adhesion;ECM-receptor interaction;Hematopoietic cell lineage;Regulates Actin and Cytoskeleton;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;
  • 功能: function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .
  • 组织表达: Liver,Placenta,
  • 科研货号: PLA004364
Cleaved-Integrin α5 LC (E895) Polyclonal Antibody
Catalog No PLA004364
Product information
  • 基因名称: ITGA5
  • 蛋白名称: Integrin alpha-5
  • Human_gene_id: 3678
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3678
  • Human_swiss_prot_no: P08648
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P08648/entry
  • Mouse_swiss_prot_no: P11688
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P11688
  • 特异性: Cleaved-Integrin α5 LC (E895) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin α5 LC protein resulting from cleavage adjacent to E895.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD antigen CD49e
  • 实测条带: 18kD
  • 信号通路: Focal adhesion;ECM-receptor interaction;Hematopoietic cell lineage;Regulates Actin and Cytoskeleton;Hypertrophic cardiomyopathy (HCM);Arrhythmogenic right ventricular cardiomyopathy (ARVC);Dilated cardiomyopathy;
  • 功能: function:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with HIV-1 Tat. Interacts with RAB21.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Membrane; Single-pass type I membrane protein. Cell junction, focal adhesion . Cell surface .
  • 组织表达: Liver,Placenta,
  • 科研货号: PLA004364
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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