Cleaved-Spectrin α II (D1185) Polyclonal Antibody

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商品货号： PLA004349

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： SPTAN1
蛋白名称： Spectrin alpha chain non-erythrocytic 1
Human_gene_id： 6709
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6709
Human_swiss_prot_no： Q13813
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13813/entry
Mouse_swiss_prot_no： P16546
Mouse_swiss_link： http://www.uniprot.org/uniprot/P16546
特异性： Cleaved-Spectrin α II (D1185) Polyclonal Antibody detects endogenous levels of fragment of activated Spectrin α II protein resulting from cleavage adjacent to D1185.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SPTAN1; NEAS; SPTA2; Spectrin alpha chain; non-erythrocytic 1; Alpha-II spectrin; Fodrin alpha chain; Spectrin, non-erythroid alpha subunit
实测条带： 137kD
信号通路： Tight junction;
功能： function:Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.,PTM:Phosphorylation of Tyr-1176 decreases sensitivity to cleavage by calpain in vitro.,similarity:Belongs to the spectrin family.,similarity:Contains 1 SH3 domain.,similarity:Contains 23 spectrin repeats.,similarity:Contains 3 EF-hand domains.,subunit:Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts with isoform 1 of ACP1. Interacts with CALM.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells. .
组织表达： Aorta,Brain,Epithelium,Fetal brain,Fetal brain cortex,Fetal liver,L
科研货号： PLA004349

Cleaved-Spectrin α II (D1185) Polyclonal Antibody

Catalog No PLA004349

Product information

基因名称： SPTAN1
蛋白名称： Spectrin alpha chain non-erythrocytic 1
Human_gene_id： 6709
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6709
Human_swiss_prot_no： Q13813
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13813/entry
Mouse_swiss_prot_no： P16546
Mouse_swiss_link： http://www.uniprot.org/uniprot/P16546
特异性： Cleaved-Spectrin α II (D1185) Polyclonal Antibody detects endogenous levels of fragment of activated Spectrin α II protein resulting from cleavage adjacent to D1185.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SPTAN1; NEAS; SPTA2; Spectrin alpha chain; non-erythrocytic 1; Alpha-II spectrin; Fodrin alpha chain; Spectrin, non-erythroid alpha subunit
实测条带： 137kD
信号通路： Tight junction;
功能： function:Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.,PTM:Phosphorylation of Tyr-1176 decreases sensitivity to cleavage by calpain in vitro.,similarity:Belongs to the spectrin family.,similarity:Contains 1 SH3 domain.,similarity:Contains 23 spectrin repeats.,similarity:Contains 3 EF-hand domains.,subunit:Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts with isoform 1 of ACP1. Interacts with CALM.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells. .
组织表达： Aorta,Brain,Epithelium,Fetal brain,Fetal brain cortex,Fetal liver,L
科研货号： PLA004349

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