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Cleaved-KLK11 (I54) Polyclonal Antibody
商品货号: PLA004330
适 应 性: 人,大鼠,小鼠,
WB ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: KLK11
  • 蛋白名称: Kallikrein-11
  • Human_gene_id: 11012
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11012
  • Human_swiss_prot_no: Q9UBX7
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q9UBX7/entry
  • Mouse_swiss_prot_no: Q9QYN3
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9QYN3
  • 特异性: Cleaved-KLK11 (I54) Polyclonal Antibody detects endogenous levels of fragment of activated KLK11 protein resulting from cleavage adjacent to I54.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: KLK11; PRSS20; TLSP; Kallikrein-11; hK11; Hippostasin; Serine protease 20; Trypsin-like protease
  • 实测条带: 25kD
  • 功能: function:Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.,PTM:About 40% of KLK11 is inactivated by internal cleavage after Arg-188. This proteolytic inactivation may be effected by plasminogen.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain; isoform 2 in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level).,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: [Isoform 1]: Secreted.; [Isoform 2]: Golgi apparatus.
  • 组织表达: Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level).
  • 科研货号: PLA004330
Cleaved-KLK11 (I54) Polyclonal Antibody
Catalog No PLA004330
Product information
  • 基因名称: KLK11
  • 蛋白名称: Kallikrein-11
  • Human_gene_id: 11012
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11012
  • Human_swiss_prot_no: Q9UBX7
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q9UBX7/entry
  • Mouse_swiss_prot_no: Q9QYN3
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9QYN3
  • 特异性: Cleaved-KLK11 (I54) Polyclonal Antibody detects endogenous levels of fragment of activated KLK11 protein resulting from cleavage adjacent to I54.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: KLK11; PRSS20; TLSP; Kallikrein-11; hK11; Hippostasin; Serine protease 20; Trypsin-like protease
  • 实测条带: 25kD
  • 功能: function:Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.,PTM:About 40% of KLK11 is inactivated by internal cleavage after Arg-188. This proteolytic inactivation may be effected by plasminogen.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain; isoform 2 in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level).,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: [Isoform 1]: Secreted.; [Isoform 2]: Golgi apparatus.
  • 组织表达: Expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 microg/mL (at protein level).
  • 科研货号: PLA004330
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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