特异性: Cleaved-Caspase-5 p20 (D121) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-5 p20 protein resulting from cleavage adjacent to D121.
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Polyclonal, Rabbit,IgG
稀释: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度: 1 mg/ml
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
其他名称: CASP5; ICH3; Caspase-5; CASP-5; ICE(rel)-III; Protease ICH-3; Protease TY
实测条带: 22kD
信号通路: NOD-like receptor;
功能: catalytic activity:Strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-Asp-|-.,function:Mediator of programmed cell death (apoptosis).,PTM:The two subunits are derived from the precursor sequence by an autocatalytic mechanism.,similarity:Belongs to the peptidase C14A family.,similarity:Contains 1 CARD domain.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10 kDa (p10) subunits.,tissue specificity:Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.,
特异性: Cleaved-Caspase-5 p20 (D121) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-5 p20 protein resulting from cleavage adjacent to D121.
组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源: Polyclonal, Rabbit,IgG
稀释: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度: 1 mg/ml
储存: -15°C to -25°C/1 year(Do not lower than -25°C)
其他名称: CASP5; ICH3; Caspase-5; CASP-5; ICE(rel)-III; Protease ICH-3; Protease TY
实测条带: 22kD
信号通路: NOD-like receptor;
功能: catalytic activity:Strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-Asp-|-.,function:Mediator of programmed cell death (apoptosis).,PTM:The two subunits are derived from the precursor sequence by an autocatalytic mechanism.,similarity:Belongs to the peptidase C14A family.,similarity:Contains 1 CARD domain.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 20 kDa (p20) and a 10 kDa (p10) subunits.,tissue specificity:Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.,