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Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody
商品货号: PLA004302
适 应 性: 人,小鼠,大鼠
WB ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: CASP2
  • 蛋白名称: Caspase2
  • Human_gene_id: 835
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=835
  • Human_swiss_prot_no: P42575
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P42575/entry
  • Mouse_swiss_prot_no: P29594
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P29594
  • 特异性: Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-2 p18 protein resulting from cleavage adjacent to G170.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1
  • 实测条带: 18 or 35kD
  • 功能: alternative products:Isoforms differ in the N- and C-termini,catalytic activity:Strict requirement for an Asp residue at P1, with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.,function:Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.,PTM:The mature protease can process its own propeptide, but not that of other caspases.,similarity:Belongs to the peptidase C14A family.,similarity:Contains 1 CARD domain.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.,tissue specificity:Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: nucleus,cytoplasm,mitochondrion,cytosol,membrane,
  • 组织表达: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
  • tag: hot
  • 科研货号: PLA004302
Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody
Catalog No PLA004302
Product information
  • 基因名称: CASP2
  • 蛋白名称: Caspase2
  • Human_gene_id: 835
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=835
  • Human_swiss_prot_no: P42575
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P42575/entry
  • Mouse_swiss_prot_no: P29594
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P29594
  • 特异性: Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-2 p18 protein resulting from cleavage adjacent to G170.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1
  • 实测条带: 18 or 35kD
  • 功能: alternative products:Isoforms differ in the N- and C-termini,catalytic activity:Strict requirement for an Asp residue at P1, with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-|-.,function:Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.,PTM:The mature protease can process its own propeptide, but not that of other caspases.,similarity:Belongs to the peptidase C14A family.,similarity:Contains 1 CARD domain.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a p18 subunit and a p12 subunit. Interacts with LRDD.,tissue specificity:Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: nucleus,cytoplasm,mitochondrion,cytosol,membrane,
  • 组织表达: Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
  • tag: hot
  • 科研货号: PLA004302
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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