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Caspase-14 Polyclonal Antibody
商品货号: PLA004301
适 应 性: 人,大鼠,小鼠,
WB ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: CASP14
  • 蛋白名称: Caspase14
  • Human_gene_id: 23581
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23581
  • Human_swiss_prot_no: P31944
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P31944/entry
  • Mouse_swiss_prot_no: O89094
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O89094
  • 特异性: Caspase-14 Polyclonal Antibody detects endogenous levels of Caspase-14 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CASP14; Caspase-14; CASP-14
  • 实测条带: 27kD
  • 功能: function:Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.,induction:In undifferentiated keratinocytes under postconfluency growth conditions (in vitro).,similarity:Belongs to the peptidase C14A family.,subunit:Complex of unprocessed caspase-14 and processed 19 kDa (p19) and 10 kDa (p10) subunits.,tissue specificity:Expressed in kerotinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus .
  • 组织表达: Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels (PubMed:11175259). The p17/10 mature form is expressed in epidermis stratum corneum, the p20/p8 intermediate form in epidermis upper granular cells of the stratum granulosum (PubMed:22825846).
  • 科研货号: PLA004301
Caspase-14 Polyclonal Antibody
Catalog No PLA004301
Product information
  • 基因名称: CASP14
  • 蛋白名称: Caspase14
  • Human_gene_id: 23581
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23581
  • Human_swiss_prot_no: P31944
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P31944/entry
  • Mouse_swiss_prot_no: O89094
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O89094
  • 特异性: Caspase-14 Polyclonal Antibody detects endogenous levels of Caspase-14 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CASP14; Caspase-14; CASP-14
  • 实测条带: 27kD
  • 功能: function:Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.,induction:In undifferentiated keratinocytes under postconfluency growth conditions (in vitro).,similarity:Belongs to the peptidase C14A family.,subunit:Complex of unprocessed caspase-14 and processed 19 kDa (p19) and 10 kDa (p10) subunits.,tissue specificity:Expressed in kerotinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus .
  • 组织表达: Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels (PubMed:11175259). The p17/10 mature form is expressed in epidermis stratum corneum, the p20/p8 intermediate form in epidermis upper granular cells of the stratum granulosum (PubMed:22825846).
  • 科研货号: PLA004301
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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