首页 > 抗体 > 一抗 > 其它 > Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody
Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody
商品货号: PLA004290
适 应 性: 人,大鼠
WB IHC IF ELISA
¥600元
规格:
在线咨询
MSDS
说明书
商品描述
  • 基因名称: CASP6
  • 蛋白名称: Caspase6
  • Human_gene_id: 839
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=839
  • Human_swiss_prot_no: P55212
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P55212/entry
  • Mouse_swiss_prot_no: O08738
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O08738
  • Rat_swiss_prot_no: O35397
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O35397
  • 特异性: Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D179.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
  • 实测条带: 20+35kD
  • 信号通路: Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;
  • 功能: catalytic activity:Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp-|-.,enzyme regulation:Activation is suppressed by phosphorylation at Ser-257.,function:Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.,PTM:Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.,similarity:Belongs to the peptidase C14A family.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus .
  • 组织表达: Lung,Lymphocyte,T-cell,
  • tag: hot
  • 科研货号: PLA004290
Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody
Catalog No PLA004290
Product information
  • 基因名称: CASP6
  • 蛋白名称: Caspase6
  • Human_gene_id: 839
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=839
  • Human_swiss_prot_no: P55212
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P55212/entry
  • Mouse_swiss_prot_no: O08738
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/O08738
  • Rat_swiss_prot_no: O35397
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O35397
  • 特异性: Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D179.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
  • 实测条带: 20+35kD
  • 信号通路: Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;
  • 功能: catalytic activity:Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp-|-.,enzyme regulation:Activation is suppressed by phosphorylation at Ser-257.,function:Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.,PTM:Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.,similarity:Belongs to the peptidase C14A family.,subunit:Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (p18) and a 11 kDa (p11) subunit.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus .
  • 组织表达: Lung,Lymphocyte,T-cell,
  • tag: hot
  • 科研货号: PLA004290
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
普拉特泽实验室电话助手

4006916686

扫码咨询