其他名称: DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
功能: RNA splicing, via transesterification reactions, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, nuclear mRNA splicing, via spliceosome, transcription, transcription, DNA-dependent, transcription initiation, RNA elongation, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter,transcription initiation from RNA polymerase II promoter, RNA elongation from RNA polymerase II promoter, RNA processing, mRNA processing, protein complex assembly, RNA splicing, mRNA metabolic process, RNA biosynthetic process, macromolecular complex subunit organization, regulation of transcription, regulation of RNA metabolic process, macromolecular complex assembly, protein complex biogenesis,
细胞定位: Nucleus . Cytoplasm . Chromosome . Hypophosphorylated form is mainly found in the cytoplasm, while the hyperphosphorylated and active form is nuclear (PubMed:26566685). Co-localizes with kinase SRPK2 and helicase DDX23 at chromatin loci where unscheduled R-loops form (PubMed:28076779). .
Total POLR2A Cell-Based Colorimetric ELISA Kit
Catalog NoPLA002044
Product information
发货日期: 14
基因名称: POLR2A
Human_gene_id: 5430
Human_swiss_prot_no: P24928
Mouse_swiss_prot_no: P08775
储存: 2-8°C/6 months
其他名称: DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)
功能: RNA splicing, via transesterification reactions, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, nuclear mRNA splicing, via spliceosome, transcription, transcription, DNA-dependent, transcription initiation, RNA elongation, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter,transcription initiation from RNA polymerase II promoter, RNA elongation from RNA polymerase II promoter, RNA processing, mRNA processing, protein complex assembly, RNA splicing, mRNA metabolic process, RNA biosynthetic process, macromolecular complex subunit organization, regulation of transcription, regulation of RNA metabolic process, macromolecular complex assembly, protein complex biogenesis,
细胞定位: Nucleus . Cytoplasm . Chromosome . Hypophosphorylated form is mainly found in the cytoplasm, while the hyperphosphorylated and active form is nuclear (PubMed:26566685). Co-localizes with kinase SRPK2 and helicase DDX23 at chromatin loci where unscheduled R-loops form (PubMed:28076779). .