功能: protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell cycle, cell cycle arrest, negative regulation of cell proliferation, regulation of cellular ketone metabolic process, phosphorylation,regulation of lipid metabolic process, regulation of fatty acid metabolic process, cell cycle process, regulation of cell proliferation, regulation of fatty acid oxidation,
细胞定位: Nucleus. Cytoplasm. Membrane . Mitochondrion. A small fraction localizes at membranes (By similarity). Relocates to the cytoplasm when bound to STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta). Translocates to the mitochondrion during apoptosis. PTEN promotes cytoplasmic localization. .; [Isoform 2]: Nucleus . Cytoplasm . Predominantly nuclear, but translocates to the cytoplasm in response to metformin or peroxynitrite treatment.
组织表达: Ubiquitously expressed. Strongest expression in testis and fetal liver.
功能: protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell cycle, cell cycle arrest, negative regulation of cell proliferation, regulation of cellular ketone metabolic process, phosphorylation,regulation of lipid metabolic process, regulation of fatty acid metabolic process, cell cycle process, regulation of cell proliferation, regulation of fatty acid oxidation,
细胞定位: Nucleus. Cytoplasm. Membrane . Mitochondrion. A small fraction localizes at membranes (By similarity). Relocates to the cytoplasm when bound to STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta). Translocates to the mitochondrion during apoptosis. PTEN promotes cytoplasmic localization. .; [Isoform 2]: Nucleus . Cytoplasm . Predominantly nuclear, but translocates to the cytoplasm in response to metformin or peroxynitrite treatment.
组织表达: Ubiquitously expressed. Strongest expression in testis and fetal liver.